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The chain rule

The chain rule differentiates a function of a function, such as (3x2 + 1)5 or esin x. It also gives dy/dx when x is written in terms of y.

The rule

If y is a function of u, and u is a function of x, then dy/dx = dy/du × du/dx.

In words: differentiate the outside, keep the inside, then multiply by the derivative of the inside.

Patterns to know

tan2 2x means (tan 2x)2, so it needs the chain rule twice.

dy/dx = 1/(dx/dy)

If x is given in terms of y, such as x = y2 + 3y or x = sin3 y, find dx/dy and take its reciprocal. You may then need to rewrite the answer in terms of x.

Worked example

Differentiate y = (3x2 + 1)5.

  1. Let u = 3x2 + 1, so y = u5.
  2. dy/du = 5u4 and du/dx = 6x.
  3. dy/dx = 5u4 × 6x

Answer: dy/dx = 30x(3x2 + 1)4

Key idea: dy/dx = dy/du × du/dx: differentiate the outside, then multiply by the derivative of the inside. dy/dx = 1/(dx/dy).

Check yourself

  1. Differentiate (2x - 1)6.
    • 6(2x - 1)5
    • 12(2x - 1)5
    • 12(2x - 1)6
    • 6(2)5
    Show answer

    12(2x - 1)5. 6(2x - 1)5 × 2 = 12(2x - 1)5.

  2. Find the gradient of y = sqrt(4x + 1) at x = 2. Give your answer as a fraction in its simplest form.
    Show answer

    2/3. y = (4x + 1)1/2, so dy/dx = (1/2)(4x + 1)-1/2 × 4 = 2/sqrt(4x + 1). At x = 2: 2/3.

  3. Differentiate ln(x2 + 1).
    • 1/(x2 + 1)
    • 2x/(x2 + 1)
    • 2x ln(x2 + 1)
    • 1/(2x)
    Show answer

    2x/(x2 + 1). d/dx ln f(x) = f'(x)/f(x), with f'(x) = 2x.

  4. Find the gradient of y = ex2 - 4x at x = 1, to 3 significant figures.
    Show answer

    -0.0996. dy/dx = (2x - 4)ex2 - 4x. At x = 1: -2e-3 = -0.0996.

  5. Differentiate cos(x2).
    • -2x sin(x2)
    • -sin(x2)
    • -sin(2x)
    • 2x sin(x2)
    Show answer

    -2x sin(x2). The outside is cos, giving -sin(x2); the inside x2 gives 2x.

  6. Differentiate tan2 2x.
    • 2tan 2x sec2 2x
    • 4sec2 2x
    • 4tan 2x sec2 2x
    • 2sec4 2x
    Show answer

    4tan 2x sec2 2x. tan2 2x = (tan 2x)2. d/dx = 2tan 2x × 2sec2 2x.

  7. x = y2 + 3y. Find dy/dx when y = 1. Give your answer as a fraction in its simplest form.
    Show answer

    1/5. dx/dy = 2y + 3 = 5, so dy/dx = 1/5.

  8. x = e2y. Find dy/dx in terms of x.
    • 2x
    • 1/(2x)
    • 1/x
    • 2e2x
    Show answer

    1/(2x). dx/dy = 2e2y = 2x, so dy/dx = 1/(2x).

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Last updated 7 November 2026. Spotted a mistake? Tell us.